Description
Chemical Name: 17ß-hydroxyandrost-4-en-3-one
Molecular Formula: C19H28O2
Molecular Weight: 288.429 gm/mol
Melting point: 155°C
Sustanon400® is an androgenic preparation for intramuscular administration containing 4 different esters of the natural hormone testosterone.
Sustanon400® is an oil based solution of four testosterone esters including those of short, intermediate, and long half-life. Serum testosterone will rapidly increase within 24 hours of intramuscular administration and remain elevated for 7-10 days. Sustanon400® is suitable for the treatment of hypogonadism and other disorders related to androgen deficiency.
Sustanon400® contains a hormone which is similar to the hormone testosterone that is produced by the body. Testosterone is a male sex hormone that is responsible for the development of male characteristics. These include growth of hair on the face and body, deepening of the voice, muscle development and the development of the male genitalia. Testosterone is also important for maintaining the strength of bones, libido and fertility in men. Men who do not produce enough testosterone may be prone to problems such as decreased libido, infertility or osteoporosis. In men who do not produce enough testosterone, Sustanon400® is used to reduce the effects of a low level of testosterone. People who have a female to male gender reassignment procedure may need to take Sustanon400® to help strengthen male characteristics.
🔬 Composition (Typical for Sustanon 400)
While the exact ester ratio can vary slightly by manufacturer, a common formulation includes:
Testosterone Ester | Amount per ml |
---|---|
Testosterone Propionate | 60 mg |
Testosterone Phenylpropionate | 120 mg |
Testosterone Isocaproate | 120 mg |
Testosterone Decanoate | 100 mg |
Total | 400 mg/ml |
Each ester has a different half-life, creating a sustained release of testosterone over time.
💉 Dosage & Administration
⚠️ Note: This information is intended for educational purposes. Actual dosage should be determined by a licensed medical provider.
⚕️ Medical TRT Use (Prescription Use)
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Typical dose: 250–500 mg every 2–4 weeks
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Route: Intramuscular (IM) injection, usually into the gluteus maximus
🏋️ Performance Enhancement (Bodybuilding Use)
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Typical dose: 400–800 mg per week (some advanced users may use 1000 mg/week or more, which increases risk)
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Cycle length: 8–12 weeks
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Often combined with: Nandrolone, Trenbolone, Dianabol, etc.
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Post Cycle Therapy (PCT): Usually required (Clomid, Nolvadex, hCG)
🧬 Pharmacokinetics
The blend allows both rapid and sustained testosterone release:
Ester | Half-Life (approx.) |
---|---|
Testosterone Propionate | 2–3 days |
Testosterone Phenylpropionate | 4–5 days |
Testosterone Isocaproate | 7–9 days |
Testosterone Decanoate | 10–14 days |
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Peak Levels: Reached within 24–48 hours for the propionate ester
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Duration: Up to 3 weeks per injection due to long esters
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Metabolism: Primarily in the liver via the 17β-hydroxysteroid dehydrogenase enzyme
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Excretion: Mainly via urine
⚠️ Side Effects
➕ Androgenic Side Effects
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Acne
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Oily skin
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Hair loss (male-pattern baldness)
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Increased body hair growth
➕ Estrogenic Side Effects
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Gynecomastia (due to aromatization to estradiol)
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Water retention
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High blood pressure
➕ Cardiovascular Risks
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Elevated LDL (bad cholesterol)
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Reduced HDL (good cholesterol)
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Increased risk of thrombosis
➕ Suppression of Natural Testosterone
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Testicular atrophy
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Infertility (due to feedback inhibition of the HPT axis)
➕ Other Possible Effects
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Mood swings
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Aggression or irritability (“roid rage”)
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Liver stress (though not as hepatotoxic as oral steroids)
❗ Warnings & Precautions
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Not recommended for individuals with prostate or breast cancer
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Use cautiously in people with heart disease, hypertension, liver or kidney disease
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Should not be used during pregnancy or breastfeeding
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Always use sterile injection techniques to avoid infection or abscess formation
📦 Storage
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Store at room temperature (15–25°C / 59–77°F)
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Protect from light and moisture
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Keep out of reach of children
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