NPP 100 mg/ml

Description

Description

Nandrolone Phenylpropionate (NPP) is an anabolic androgenic steroid (AAS), derived from testosterone. It is a short-ester variant of nandrolone, differing from Nandrolone Decanoate (Deca-Durabolin) mainly in the ester, which affects how quickly it is released into the bloodstream. It is typically found in 100 mg/ml injectable form.

• Chemical Name: 19-nortestosterone phenylpropionate

• Molecular Formula: C27H34O3

• Anabolic:Androgenic Ratio: ~125:37

• Half-life: ~2–4 days

• Detection Time: ~12 months

2. Medical & Performance Usage

Medical Use

NPP has been used clinically for:

• Treatment of muscle wasting diseases

• Anemia

• Osteoporosis

• Severe burns

• Hormonal therapy (off-label in some cases)

Performance/Bodybuilding Use (Note: non-medical use may be illegal depending on jurisdiction)

• Muscle growth (lean mass)

• Increased strength

• Enhanced recovery

• Joint relief (due to increased synovial fluid retention)

3. Dosage & Administration

Medical Dosage

• Varies depending on condition: typically 50–100 mg every 3–4 days.

Bodybuilding Dosage (for informational purposes only)

• Men: 100–200 mg every other day or 300–600 mg/week, split into multiple injections due to short half-life.

• Women: 25–50 mg/week (though risk of virilization is high, and use is generally discouraged).

Route of Administration: Intramuscular injection
Frequency: Due to the phenylpropionate ester, injections are commonly done every other day or 3x per week.

4. Side Effects

Androgenic Effects

• Acne

• Hair loss (in genetically predisposed individuals)

• Increased body/facial hair

• Deepening of the voice (especially in females)

Estrogenic Effects (via aromatization to estradiol)

• Water retention

• Gynecomastia

• Elevated blood pressure
  (These can be mitigated with an aromatase inhibitor)

Other Possible Effects

• Suppression of natural testosterone production

• Altered cholesterol levels (reduced HDL, increased LDL)

• Liver toxicity (minimal as it’s not 17-alpha alkylated)

• Aggression or mood swings

In Females

• High virilization risk: voice changes, clitoral enlargement, body hair growth, menstrual irregularities

5. Pharmacokinetics

• Absorption: Rapid after intramuscular injection due to the short ester

• Onset of Action: Within 24–48 hours

• Half-life: Approximately 2–4 days

• Peak Levels: ~24–48 hours post-injection

• Metabolism: Primarily in the liver, via reduction and conjugation

• Excretion: Renal (urine)

Important Notes

• PCT (Post Cycle Therapy) is recommended after discontinuing use to restore natural testosterone production.

• Not approved for over-the-counter use; typically prescription-only in countries where legal.

• WADA-banned substance: Not allowed in competitive sports.